T. C. Grant enters the Foggia semi-finals as the higher-ranked player at No. 184, competing on home clay in Italy. The Italian has shown mixed form heading into this matchup, posting a recent record of one loss and two wins, including victories over V. Lepchenko and L. Zaar in straight sets. Grant is favoured at 1.32 in decimal odds on Pinnacle, reflecting her seeding advantage. This is the first career meeting between Grant and D. Astakhova.

D. Astakhova arrives at the Foggia semi-finals ranked No. 277 on the WTA ladder, seeking an upset on Italian clay. The player has maintained winning form through the event with consecutive victories over L. Pigato (2–1) and X. Gao (0–2), demonstrating strong performances in both close and dominant matches. Astakhova faces long odds at 3.55 to advance but carries momentum into the final four. The all-time head-to-head record between these players stands level at 0–0.